Welcome to Algorithmic Biology Laboratory: ABL research focuses on quantitative modeling of various life phenomena at cellular and molecular levels. In particular, ABL research includes modeling RNA structure and ncRNA-mRNA interactions, de novo assembly of short and long sequencing reads for genomic and transcriptomic studies, de novo genomic variation detection, and synthetic biology. ABL is directed by Prof. Chitsaz and is located in the Maccabees Building on Wayne State University campus.

Single Cell Genomics Our single cell assembly paper entitled "Efficient de novo assembly of single-cell bacterial genomes from short-read data sets" has been published in Nature Biotechnology. We modified Velvet to obtain Velvet-SC for MDA single cell data. Camel Released We have released Camel, a tool for correcting substitution errors in Illumina reads, particularly designed for single cell MDA DNA. Camel is available in our softwares section.